Clinical manifestation/diagnosis of nephropathy
نویسنده
چکیده
A quarter of the cardiac output is consigned to the perfusion of the kidneys – even though the kidneys amount to just 0.5 % of the total body weight. Approximately every 20 minutes, i.e. 70 times a day, the entire blood plasma is filtered by the kidneys. Therefore, kidney glomeruli are target organs for every hematogenous infection. Viral infection can cause primary glomerulonephritis, whereas an immune reaction can lead to secondary glomerulonephritis. HIV infection, hepatitis B and C as well as bacterial infections are all typical causes of renal disease. Nephrotoxic agents precipitate renal diseases that affect the interstitium and the tubular apparatus in particular, and these have to be differentiated from glomerulonephritis.
منابع مشابه
Clinical, Histopathological and Immunofluorescent Findings of IgA Nephropathy
Background: IgA nephropathy, a prevalent disease in Asia, is considered the main cause of end stage renal disease among primary glomerular disease. Objective: To determine the frequency of different clinical, histopathological and immunofluorescent characteristics of IgA nephropathy. Methods: Renal biopsies of 376 patients were received for immunofluorescent and for histopathological studies. B...
متن کاملIgA nephropathy in systemic lupus erythematosus.
Renal involvement in systemic lupus erythematosus (SLE) is a typical manifestation of the disease. The occurrence of non-lupus nephritis in SLE patients has rarely been reported; we describe the case of a woman suffering from SLE and IgA nephropathy (IgAN). Although IgAN and lupus nephritis share some common physiopathological characteristics, their laboratory and histopathologic findings and t...
متن کاملLambda Light Chain Crystalline Cast Nephropathy and Proximal Tubulopathy
INTRODUCTION P lasma cell dyscrasias such as multiple myeloma (MM) result from clonal proliferation of plasma cells and subsequent overproduction of Igs, including free light chains. Renal dysfunction is a core manifestation of plasma cell dyscrasias. A broad range of kidney pathologies can occur, including light chain cast nephropathy, monoclonal Ig deposition disease, light chain amyloidosis,...
متن کاملPetechial Hemorrhage: A clinical diagnosis of neonatal Thrombocytopenia and sepsis
A preterm female baby with birth weight of 1.5kg was referred to our hospital on day 6 for difficulty in breathing. Baby was admitted at birth for respiratory distress and feed intolerance to other hospital and in view of clinical deterioration baby was referred. Baby had thrombocytopenia with platelets counts of 11000/ mm3 and high CRP titer. Baby had petechial haemorrhagic spots all over the ...
متن کاملIs there a pathogenic association between Fabry’s disease and IgA nephropathy?
Several cases of concurrent Fabry's disease and IgA nephropathy have been reported, but the pathogenic association between these two diseases remains unclear. This is a report on the case of a girl with severe IgA nephropathy who was subsequently diagnosed with subclinical Fabry's disease. An 11-year-old girl was admitted to our hospital with massive proteinuria and hematuria detected by urinar...
متن کاملAcyclovir Nephrotoxicity: A Case Report Highlighting the Importance of Prevention, Detection, and Treatment of Acyclovir-Induced Nephropathy
Acute kidney injury is an unfortunate complication of acyclovir therapy secondary to crystal-induced nephropathy. It is characterized by a decrease in renal function that develops within 24-48 hours of acyclovir administration indicated by a rapid rise in the serum creatinine. Failure to quickly realize this as an etiology of acute kidney injury can lead to excessive morbidity to the patient. T...
متن کامل